USA TODAY Sports' Week 1 NFL picks

Week 1 of the NFL season starts Thursday.

The schedule begins with the Denver Broncos hosting the Carolina Panthers in a Super Bowl 50 rematch, with the Broncos being the rare defending champion to open as an underdog.

Week 1 concludes with a Monday Night Football doubleheader that will finish with the Rams playing their first game representing Los Angeles since 1994 against the San Francisco 49ers.